Living with chronic conditions like psoriasis or psoriatic arthritis isn’t just about managing symptoms—it’s about reclaiming control. For many, apremilast (Aprezo) has been a helpful to dial down inflammation and improve daily life.
But here’s the deal: your lifestyle choices can make or break your experience on this medication.
What you eat, how you move, and even how well you sleep directly affect its effectiveness. This isn’t about perfection—it’s about smart, research-backed strategies to help you feel better, move easier, and live fully while on apremilast.
Why diet and lifestyle matter with apremilast
Apremilast works by targeting inflammation, and your daily habits either support or undermine this process. While the skincare medication is doing its job, you can level up your results by making choices that amplify its effects and minimize side effects.
The right lifestyle while you’re on apremilast
1. Eat for Less Inflammation, More Relief
Your diet is a powerful tool in fighting inflammation. The goal? Stack the odds in your favor.
Some foods can calm the immune system:
| What to Load Up On | Recommendation |
|---|---|
| Fatty Fish | Salmon, mackerel, sardines—they’re packed with omega-3s, which help lower inflammation. |
| Leafy Greens | Kale, spinach, Swiss chard—loaded with antioxidants to fight oxidative stress. |
| Berries | Blueberries, strawberries—they’re nature’s anti-inflammatory powerhouses. |
| Whole Grains | Ditch the white bread and opt for quinoa, brown rice, or whole wheat to keep inflammation in check. |
| Nuts & Seeds | Almonds, walnuts, and flaxseeds bring healthy fats and fiber to the table. |
On the other hand, some types can set it off like an alarm.
Data from several phase III clinical trials and real-world studies showed a good benefit-risk profile, with diarrhea and nausea as the most common adverse events. Diarrhea and nausea most frequently occurred during the first month of treatment. In most cases, they were mild or moderate in severity and tended to resolve over time with continued dosing and without intervention (Gastrointestinal side effects of apremilast : Characterization and management – PubMed).
| What to Cut Back On | Why Avoid Them? |
|---|---|
| Sugary drinks & processed snacks | These spike inflammation and can trigger flare-ups. |
| Red & processed meats | Linked to higher inflammation levels—keep it minimal. |
2. Beat Side Effects with Smart Nutrition
Apremilast can cause digestive issues, especially in the early weeks. Don’t worry—you can hack your diet to stay ahead of them.
| Diet Hack | Why Do This? |
|---|---|
| Stay Hydrated | Water is your best defense against dehydration from diarrhea. |
| Ginger Tea | A natural nausea remedy that soothes the stomach. |
| The BRAT Diet | Bananas, rice, applesauce, and toast—simple foods to calm an upset stomach. |
| Small, Frequent Meals | Eating smaller portions more often helps prevent nausea. |
3. Move Smart: Exercises That Help, Not Hurt
Exercise is a powerhouse—not just for fitness, but for tackling inflammation and keeping your joints in check. The secret? Move smarter, not harder.
| Exercise Tip | Recommended Practice |
|---|---|
| Go Low-Impact | Forget punishing workouts. Yoga, swimming, and walking give you all the benefits without the strain. |
| Stretch Daily | Mobility is the real deal. A few minutes of stretching keeps stiffness at bay and helps you move freely, not painfully. |
| Consistency Beats Intensity | A solid 20–30 minutes a day wins every time over the occasional all-out session. Slow and steady? That’s the way to go. |
4. Stress: The Hidden Trigger You Can’t Ignore
Stress doesn’t just mess with your head—it fires up inflammation and worsens symptoms. You need to learn how to manage it effectively and here are some ways to do it:
| How to Manage Stress | Why Do This? |
|---|---|
| Try Mindfulness & Meditation | Just 10 minutes a day can rewire your brain for calm. Start small and build from there. |
| Journal It Out | Thoughts on paper = less stress in your system. Science backs it up. |
| Stay Connected | Family, friends, support groups. Isolation fuels stress. Don’t go doing it alone. |
Having psoriasis alone can cause you stress which is why it’s important for you to know to handle it while using this medication.
Reports of suicidal ideation due to apremilast are rare and no difference was reported against placebo in the randomized‐controlled trials. The significance of this symptom, in addition to the knowledge that depression, is a known comorbidity of psoriasis, justifies close monitoring of patients on apremilast (Mental health, insomnia and suicidal ideation during treatment with apremilast – PMC).
5. Sleep: Your Body’s Best Reset Button
Want to feel better? Fix your sleep. Your body heals, restores, and fights inflammation while you rest. Make it count.
| Sleeping Tip | Why Do This? |
|---|---|
| Stick to a Schedule | Same bedtime, same wake-up time—your body thrives on routine. |
| Ditch the Screens | Blue light wrecks melatonin levels. Power down at least an hour before bed. |
| Create a Sleep Haven | Preferably one that’s cool, dark and quiet. Your room should be a recovery zone, not a distraction hub. |
Start taking control of your health
Managing a chronic condition is tough, but you have options. Apremilast can help—but pairing it with smart habits (nutrition, movement, stress management) makes the difference.
Every step toward a healthier lifestyle is a step toward feeling better. Start today. Your future self will thank you.
Where to buy apremilast
Here are the most reliable and trusted sites where you can purchase apremilast (Aprezo):
| HealthyRXs | ✅ Discounted prices ✅ Free shipping on orders over $200 |
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| ReliableRxPharmacy | ✅ Quick and easy ordering ✅ Reliable customer service |
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